MCCQE Exam Dumps - Medical Council of Canada MCCQE Part 1 Questions and Answers

The first step in evaluating a new, hot, swollen joint is arthrocentesis to rule out septic arthritis and crystal arthropathy. Joint aspiration provides fluid for microscopy, culture, and crystal analysis, which guides definitive diagnosis and treatment.

Toronto Notes 2023 – Rheumatology, Monoarthritis:

“Joint aspiration is the most important first step in evaluating monoarthritis. Septic arthritis must be ruled out before initiating any therapy.”

MCCQE1 Objectives – Internal Medicine > Rheumatology:

“Candidates should perform joint aspiration in the presence of acute monoarthritis to differentiate between septic arthritis, gout, and other causes.”

Radiography (A) and serum uric acid (B) do not establish cause acutely. Empiric antibiotics (D) and NSAIDs (E) should only be started after ruling out septic arthritis.

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Comprehensive and Detailed Explanation:

Basement apartments are often damp environments, increasing the risk of mold exposure. Mold is a well-known asthma trigger. Given the timing (autumn/winter) and environment change, mold allergy is the most likely cause.

Toronto Notes 2023 – Respirology / Allergy:

“Mold is a common indoor allergen, especially in damp environments. It frequently exacerbates asthma, particularly in fall/winter.”

MCCQE1 Objectives (Pediatrics > 75-2: Asthma Triggers):

“Candidates must identify common environmental triggers for asthma, including mold exposure in humid or poorly ventilated housing.”

Cat allergy (B) would have triggered earlier. Pollen (D) is less relevant in winter. Cold intolerance (E) is not a major asthma trigger without exercise. Fungal infection (A) is unlikely without systemic symptoms.

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This clinical picture suggests giant cell arteritis (GCA) associated with polymyalgia rheumatica: new-onset headache in an older patient, proximal muscle pain and stiffness (shoulders and hips), systemic symptoms (weight loss), and mood changes. MCCQE objectives emphasize that GCA is a medical emergency because inflammation of the temporal and other cranial arteries can lead to irreversible vision loss due to ischemic optic neuropathy.

The most important objective of treatment is prevention of blindness , which requires prompt initiation of high-dose corticosteroids—often before confirmatory temporal artery biopsy—to reduce arterial inflammation and prevent vascular occlusion. While improving musculoskeletal pain and headache are important symptomatic goals, they are secondary to preventing permanent complications. Jaw claudication is a symptom of arterial insufficiency but not itself the primary outcome to prevent.

Early recognition and immediate corticosteroid therapy significantly reduce the risk of bilateral, permanent visual loss. Therefore, prevention of blindness is the most critical treatment objective.

Chlamydia trachomatis is the most common cause of cervicitis in young sexually active women and frequently presents with dysuria, dyspareunia, intermenstrual bleeding, and a normal vulvovaginal exam. It may be asymptomatic or have subtle signs and often affects the endocervix.

Toronto Notes 2023 – Gynecology, “Sexually Transmitted Infections” Section:

“Chlamydia is the most common bacterial STI. Symptoms may include intermenstrual bleeding, postcoital bleeding, dyspareunia, mucopurulent cervical discharge, and dysuria. The vulva and vagina may appear normal.”

MCCQE1 Objectives (Obstetrics and Gynecology > 82-1: Abnormal Uterine Bleeding):

“Candidates should evaluate STI-related cervicitis as a common cause of postcoital and intermenstrual bleeding in young women.”

Other options:

A. Actinomyces israelii is associated with IUD use, not relevant here.

B. Herpes simplex virus usually presents with painful ulcerations, not abnormal bleeding.

C. Treponema pallidum (syphilis) causes painless ulcers or systemic symptoms in later stages.

D. HPV causes warts or asymptomatic cervical dysplasia, not acute symptoms.

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